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    Hepatitis A + B (combination) – adults

    Combination vaccine that protects against both hepatitis A and B.

    Protects against

    Hepatitis A and B

    Validity

    Lifelong for HBV, >30 years for HAV

    Schedule

    3 doses: 0, 1 and 6 months

    Side effects

    Usually mild

    About Hepatitis A and B

    This combination vaccine protects against two different forms of liver inflammation. Hepatitis A spreads through contaminated food and water; hepatitis B through blood and body fluids. Both can cause serious illness.

    How is it transmitted?

    Hepatitis A: fecal-oral route (contaminated food/water). Hepatitis B: blood and body fluids (sexual contact, needles, medical procedures).

    Symptoms

    Fatigue
    Abdominal pain
    Nausea and vomiting
    Jaundice
    Dark urine
    Joint pain (especially HBV)

    Possible complications

    • Hepatitis A: prolonged fatigue, rarely liver failure
    • Hepatitis B: chronic infection, liver cirrhosis, liver cancer

    Risk areas

    AfricaAsiaCentral and South AmericaEastern EuropePacific islands

    About the vaccination

    Vaccine type

    Combination vaccine (inactivated HAV + recombinant HBV)

    How does it work?

    The vaccine combines the active ingredients of both vaccines in one injection, so you are fully protected with fewer injections.

    ⏱️ When to vaccinate?

    Ideally 6 months before departure. Accelerated schedule available for hepatitis B component.

    Effectiveness

    Very high for both components.

    Who should get this vaccination?

    • Travelers who need protection against both diseases
    • Long-term residents in risk areas
    • People who regularly travel to risk areas

    Not suitable for

    • People with severe allergic reaction to components
    • People with severe acute illness

    Possible side effects

    Similar to separate vaccines: local reactions, fatigue.

    Book an appointment?

    Contact us for personal advice about your vaccinations.

    Personal care

    We respect your preferences. You can choose a male or female practitioner.

    Short waiting time

    Usually available within a week. Call for urgent appointments.

    View pricing

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    Destinations where this vaccination is relevant

    Check the full advice for your destination.

    All destinations →

    Need more vaccinations?

    View all travel vaccinations we offer or book an appointment for personal advice.